Aloe Vera Helps Fights Skin Cancer
A number of new studies are showing that Aloe vera can both prevent and even treat melanoma.
Aloe-emodin stops skin cancer growth
Aloe-emodin is a compound found in Aloe. Turns out this compound can halt the growth of skin cancer cells.
Research from the University of Belgrade’s School of Medicine confirmed what previous studies on Aloe-emodin found. The biochemical inhibit the process of skin cancer growth – also called cancer cell proliferation.
The researchers tested Aloe-emodin on human skin cells called keratinocytes after being treated with radiation. Once radiated, keratinocytes will typically proliferate (expand) into skin cancer tumors.
The researchers found that the Aloe-emodin significantly stopped the proliferation process. This confirmed Aloe’s benefit in halting the progression of tumor formation after radiation by the sun.
Other studies confirm Aloe anticancer effect
A similar result was found by researchers from South Korea’s Gachon University of Medicine and Science. They determined that Aloe-emodin specifically halted the growth of human cancerous liver cells. The researchers found that Aloe-emodin stimulated a genetic change within the cancerous cells that not only halted their expansion, but induced cell death among the cancer cells.
Researchers from Sree Chitra Tirunal Institute for Medical Sciences and Technology found that Aloe-emodid was able to inhibit the growth of colon cancer cells. The Aloe-emodin also induced cell death among the individual cancer cells.
These studies of human cells confirm similar findings in animal research – showing the application of Aloe vera gel onto the skin significantly inhibits the progression of skin cancer.
China Medical University researchers determined that another Aloe constituent called Rhein also produced anticancer effects. They found that tumor progression was halted and cancer cell death occurred as a result of Rhein.
Capasso R, Laudato M, Borrelli F. Meeting report: First National Meeting on Aloe, April 20-21, 2013, Isernia, Italy. New perspectives in Aloe research: from basic science to clinical application. Nat Prod Commun. 2013 Sep;8(9):1333-4.
Popadic D, Savic E, Ramic Z, Djordjevic V, Trajkovic V, Medenica L, Popadic S. Aloe-emodin inhibits proliferation of adult human keratinocytes in vitro. J Cosmet Sci. 2012 Sep-Oct;63(5):297-302.
Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. Int J Toxicol. 2007;26 Suppl 2:1-50.
Saini M, Goyal PK, Chaudhary G. Anti-tumor activity of Aloe vera against DMBA/croton oil-induced skin papillomagenesis in Swiss albino mice. J Environ Pathol Toxicol Oncol. 2010;29(2):127-35.