Medicinal Effects of Allspice Herb

Allspice, scientifically known as Pimenta dioica, is a versatile spice with various medicinal benefits. Allspice is also commonly referred to as Pimento and Jamaican Pepper. This herb has a number of medicinal properties. This includes being an antifungal, antibacterial, anti-inflammatory and antiseptic herb.

Allspice (Pimenta dioica)


What is Allspice?

Allspice is derived from the dried berries of the allspice tree, native to Central and South America, particularly the Caribbean region. It also grows in Japan and parts of Asia. 

The tree bears glossy, dark green leaves and clusters of small white or yellow flowers. Its round berries resemble peppercorns.

Compounds in Allspice

The primary compounds in allspice include eugenol, cineole, myrcene, and quercetin. In addition there are a number of monoterpenes, sesquiterpenes, flavonoids, organic acids, alkaloids and monoterpenoid phenols in allspice.

These compounds together contribute to its antioxidant, anti-inflammatory, antimicrobial, and digestive properties.

Allspice in Traditional Medicine

In traditional medicine practices globally, allspice has been utilized for various purposes:

Digestive Aid

Allspice has been used to aid digestion, relieve gas, and soothe stomach discomfort.

Pain Relief

The eugenol content in allspice has analgesic properties, making it useful for alleviating toothaches, muscle aches, and joint pain.

Antimicrobial Action

Allspice exhibits antimicrobial properties, which may help fight against bacterial and fungal infections.

Anti-inflammatory Effects

Research suggests that allspice may possess anti-inflammatory properties, potentially beneficial for conditions like arthritis and inflammatory bowel diseases.

Research evidence

A 2021 study tested allspice extracts and found that they had significant antifungal properties. The research found the herb inhibited mycelial growth and the germination of fungus spores. The herb also changed the shape of the fungal microbes.

A 2025 study from Ottawa Ontario found that allspice extracts were significantly antiviral, even to COVID-19 related viruses. The researchers found allspice extracts blocked the ability of SARS-CoV-2 proteins to ACE2. This is one of the primary mechanisms for the growth of SARS in humans. The research also found these abilities were dose-dependent, eliminating the potential for coincidence. The researchers stated:

“These findings support the potential allspice utilization in reducing the risk of SARS-CoV-2 virus infection and the development of COVID-19 severe symptoms.”

In a 2024 study, researchers found that allspice extract significantly reduced concentrations of Helicobacter pylori. H. pylori has been implicated in a number of digestive tract issues, including certain ulcers and stomach cancers.

2022 Research from Italy and Saudi Arabia found that allspice extracts were significantly antibacterial against sometimes-lethal bacteria such as Listeria monocytogenes and Pseudomonas aeruginosa. The research found that not only did the allspice extracts inhibit the growth of these and other bacteria: The extracts also interfered with the quorum sensing abilities of the bacteria.

Bacteria use quorum sensing to communicate and understand their environment.

A 2023 study confirmed allspice extracts’ ability to control listeria microbes.

A 2018 study found that allspice can inhibit the growth of various fungi that can infect grains and seeds in storage. One of these is alflatoxin B1 – from the Aspergillus flavus species.

Other research has found allspice to be an successful natural pesticide as well.

Studies have also found that allspice can be added to fish stocks to help prevent diseases without chemical antibiotics.

2007 research from Egypt found that allspice extracts killed cancer cells and inhibited the growth of tumors. A 2021 study from Brazil confirmed this research.

Other studies have investigated allspice extracts’ ability to deter wound infection. A 2020 study found the extracts blocked and reduced bacteria biofilms from wounds.

2021 research from Mexico found that allspice extracts killed the eggs and larva of parasites in the digestive tracts of sheep and cattle.

While traditional uses of allspice are well-documented, there is limited clinical research specifically on its health benefits. Yet studies on its individual components such as eugenol have demonstrated allspice’s promising health benefits.

As usual, talk with your doctor before employing herbs for medicinal purposes.

Scientific References

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Zhang L, Shamaladevi N, Jayaprakasha GK, Patil BS, Lokeshwar BL. Polyphenol-rich extract of Pimenta dioica berries (Allspice) kills breast cancer cells by autophagy and delays growth of triple negative breast cancer in athymic mice. Oncotarget. 2015 Jun;6(18):16379-16395. doi: 10.18632/oncotarget.3834. PMID: 25945840; PMCID: PMC4599276.

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Lee DH, Lee MW, Cho SB, Hwang K, Park IK. Antifungal mode of action of bay, allspice, and ajowan essential oils and their constituents against Colletotrichum gloeosporioides via overproduction of reactive oxygen species and downregulation of ergosterol biosynthetic genes Industrial crops and products.. 2023 Jul;197:Not Available. AGR:IND608019712.

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